Vol 5: A gain-of-function mutant p53-HSF1 feed forward circuit governs adaptation of cancer cells to proteotoxic stress.Report as inadecuate



 Vol 5: A gain-of-function mutant p53-HSF1 feed forward circuit governs adaptation of cancer cells to proteotoxic stress.


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This article is from Cell Death & Disease, volume 5.AbstractTo overcome proteotoxic stress inherent to malignant transformation, cancer cells induce a range of adaptive mechanisms, with the master transcription factor heat-shock factor 1 (HSF1)-orchestrated response taking center stage. Here we define a novel gain-of-function of mutant p53 (mutp53)

Author: Li, D; Yallowitz, A; Ozog, L; Marchenko, N

Source: https://archive.org/







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