Vol 3: AFF4 binding to Tat-P-TEFb indirectly stimulates TAR recognition of super elongation complexes at the HIV promoter.Report as inadecuate



 Vol 3: AFF4 binding to Tat-P-TEFb indirectly stimulates TAR recognition of super elongation complexes at the HIV promoter.


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This article is from eLife, volume 3.AbstractSuperelongation complexes (SECs) are essential for transcription elongation of many human genes, including the integrated HIV-1 genome. At the HIV-1 promoter, the viral Tat protein binds simultaneously to the nascent TAR RNA and the CycT1 subunit of the P-TEFb kinase in a SEC. To understand the preferent

Author: Schulze-Gahmen, Ursula; Lu, Huasong; Zhou, Qiang; Alber, Tom

Source: https://archive.org/







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