Vol 9: Active-State Model of a Dopamine D2 Receptor - Gi Complex Stabilized by Aripiprazole-Type Partial Agonists.Report as inadecuate



 Vol 9: Active-State Model of a Dopamine D2 Receptor - Gi Complex Stabilized by Aripiprazole-Type Partial Agonists.


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This article is from PLoS ONE, volume 9.AbstractPartial agonists exhibit a submaximal capacity to enhance the coupling of one receptor to an intracellular binding partner.
Although a multitude of studies have reported different ligand-specific conformations for a given receptor, little is known about the mechanism by which different receptor confor

Author: Kling, Ralf C.; Tschammer, Nuska; Lanig, Harald; Clark, Timothy; Gmeiner, Peter

Source: https://archive.org/



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