Vol 4: Facet-Specific Assembly of Proteins on SrTiO3 Polyhedral Nanocrystals.Report as inadecuate



 Vol 4: Facet-Specific Assembly of Proteins on SrTiO3 Polyhedral Nanocrystals.


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This article is from Scientific Reports, volume 4.AbstractPrecisely controlling the protein-nanomaterial interactions at selective sites is crucial in engineering biomolecule composite architectures with tailored nanostructures and functions for a variety of biomedical applications. This strategy, however, is only beginning to be explored. Here, we demonstrate the facet-specific assembly of proteins, such as albumin, immunoglobulin and protamine, on {100} facets of SrTiO3 polyhedral nanocrystals, while none on {110} facets. Molecular dynamics simulations indicate the immobile surface hydration layer might play a barrier role to effectively prevent proteins adsorption on specific {110} facets. This work thus provides new insights into the fundamentally understanding of protein-nanomaterial interactions, and open a novel, general and facile route to control the selective adsorption of various proteins on various nanocrystals.



Author: Dong, Lingqing; Luo, Qi; Cheng, Kui; Shi, Hui; Wang, Qi; Weng, Wenjian; Han, Wei-Qiang

Source: https://archive.org/



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