Fatal transfusion related acute lung injury following coronary artery by-pass surgery: a case reportReport as inadecuate




Fatal transfusion related acute lung injury following coronary artery by-pass surgery: a case report - Download this document for free, or read online. Document in PDF available to download.

Cases Journal

, 1:372

First Online: 03 December 2008Received: 07 November 2008Accepted: 03 December 2008DOI: 10.1186-1757-1626-1-372

Cite this article as: Bawany, F.A. & Sharif, H. Cases Journal 2008 1: 372. doi:10.1186-1757-1626-1-372

Abstract

BackgroundTransfusion related acute lung injury TRALI is a potentially fatal Acute Lung Injury following transfusion of blood components. Hypotheses implicate donor-derived anti-human leukocyte antigen or granulocyte antibodies reacting with recipients- leukocytes, releasing inflammatory mediators. Lack of agreement on underlying cellular and molecular mechanisms renders improving transfusion safety difficult and expensive.

Case PresentationLiterature search has not revealed any case of TRALI from Pakistan. We report the case of fatal TRALI in a 68 year old male who received blood products after coronary artery by-pass surgery.

ConclusionThis article aims to create awareness about this complication and suggests that post transfusion cardiopulmonary instability should alert to the possibility of TRALI.

AbbreviationsTRALITransfusion Related Acute Lung Injury

ALIAcute Lung Injury

CADCoronary artery Disease

CABGCoronary Artery By-pass Surgery

CDCluster of Differentiation

HLAHuman Leukocyte Antigen.

Download fulltext PDF



Author: Fauzia Ahmad Bawany - Hasanat Sharif

Source: https://link.springer.com/



DOWNLOAD PDF




Related documents