Factors associated with poor prognosis among patients admitted with heart failure in a Nigerian tertiary medical centre: a cross-sectional studyReport as inadecuate




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BMC Cardiovascular Disorders

, 8:16

First Online: 22 July 2008Received: 06 February 2008Accepted: 22 July 2008DOI: 10.1186-1471-2261-8-16

Cite this article as: Karaye, K.M. & Sani, M.U. BMC Cardiovasc Disord 2008 8: 16. doi:10.1186-1471-2261-8-16

Abstract

BackgroundHeart failure is a major and growing public health problem worldwide. The prognosis of Heart Failure HF is uniformly poor despite advances in treatment. The aims of the present study were to determine the causes of HF among patients admitted to a Nigerian tertiary medical centre, to determine the prevalence of factors known to be associated with poor prognosis among these patients, and to compare the factors and causes between males and females.

MethodsThe study was cross-sectional in design, carried out on eligible patients who were consecutively admitted with HF, in Aminu Kano Teaching Hospital, Kano, Nigeria. The following established factors associated with poor prognosis of HF were assessed: low Left Ventricular Ejection Fraction LVEF of ≤ 40%, anaemia, renal impairment, cardiac rhythm disturbances on the electrocardiogram, prolonged corrected QT interval QTc, complete Left Bundle Branch Block LBBB and advanced age.

ResultsA total of 79 patients were studied over a six-month period. Forty four 55.7% of these patients were males while the remaining 35 44.3% were females. The most prevalent prognostic factor was low LVEF found in a total of 35 patients 44.3%, while the least prevalent was complete LBBB found in two male patients only 2.53%. The commonest cause of heart failure in all patients and males was hypertensive heart disease, found in a total of 45 patients 57.0%, comprising of 33 male 73.3% and 12 female patients 26.7% p = 0.0003. Cardiomyopathies were the commonest causes in females, the predominant type being peripartum cardiomyopathy found in 11 31.4% female patients. Acute myocardial infarction has emerged to be an important cause of HF in males 13.6% with a high in-hospital mortality of 66.7%.

ConclusionThe most prevalent factor associated with poor prognosis was low LVEF. Hypertensive heart disease and cardiomyopathies were the most common causes of HF in males and females respectively. The findings of the study should guide decision-making regarding management of HF patients.

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Author: Kamilu M Karaye - Mahmoud U Sani

Source: https://link.springer.com/



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