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BMC Cardiovascular Disorders

, 16:228

Hypertension and Cardiovascular Risk

Abstract

BackgroundMetabolic syndrome MetS is correlated with arterial stiffness and can be evaluated by brachial-ankle pulse wave velocity baPWV. We investigated potential associations between MetS and baPWV in a Chinese community population.

MethodsThe community-based Asymptomatic Polyvascular Abnormalities in Community study examined asymptomatic polyvascular abnormalities in a Chinese population aged ≥40 years. The relationship between MetS and its components and baPWV was analyzed by multivariate logistic and linear regression models.

ResultsOut of 5181 study participants, 1271 subjects 24.53% had MetS. Mean values of baPWV in subjects with 0, 1, 2,3, 4, and 5 components of MetS were 1430, 1526, 1647, 1676,1740, and 1860 cm-s, respectively p < 0.001 for trend. After adjusting for confounding risk factors, MetS was significantly associated with baPWV odds ratio OR: 2.74; 95% CI: 2.28, 3.30. Among the five components of MetS, elevated blood pressure was the most important factor for baPWV. All models of multivariate linear regression analysis showed a significant positive correlation between the increasing numbers of MetS components and baPWV p < 0.0001.

ConclusionsbaPWV was associated with MetS and was greater with increasing numbers of MetS components. Elevated blood pressure was the most important factor for baPWV.

KeywordsBrachial-ankle pulse wave velocity Metabolic syndrome Arterial stiffnes Cardio-cerebrovascular diseases AbbreviationsAPACAsymptomatic polyvascular abnormalities community

baPWVbrachial-ankle pulse wave velocity

BMIBody mass index

BPBlood pressure

CIConfidence internals

HDL-CHigh-density lipoprotein cholesterol

LDL-CLow-density lipoprotein cholesterol

MetSMetabolic syndrome

OROdds ratio

SDStandard deviation

TGTriglyceride

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Author: Anxin Wang - Zhaoping Su - Xiaoxue Liu - Yuling Yang - Shuohua Chen - Suzhen Wang - Yanxia Luo - Xiuhua Guo - Xingquan Zh

Source: https://link.springer.com/







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