Diabetes Mellitus in Pancreatic Cancer Patients in the Czech Republic: Sex DifferencesReport as inadecuate




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Experimental Diabetes ResearchVolume 2012 2012, Article ID 414893, 5 pages

Research Article

Department of Internal Medicine and Gastroenterology, University Hospital and Faculty of Medicine, Masaryk University Brno, Jihlavska 20 62500 Brno, Czech Republic

University of North Dakota, Grand Forks, ND 58202, USA

Department of Pathology, University Hospital and Faculty of Medicine, Masaryk University Brno, 62500 Brno, Czech Republic

Received 20 December 2011; Revised 21 March 2012; Accepted 8 May 2012

Academic Editor: Chin-Hsiao Tseng

Copyright © 2012 Jan Trna et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Aims. The prevalence of diabetes mellitus in pancreatic cancer patients and control subjects was compared. Methods. Retrospective evaluation of 182 pancreatic cancer patients and 135 controls. The presence of diabetes was evaluated and the time period between the diagnosis of diabetes and pancreatic cancer was assessed. A subanalysis based on patient sex was conducted. Results. Diabetes mellitus was present in 64 patients 35.2% in pancreatic cancer group and in 27 patients 20.0% in control group ; . In 18 patients 28.1% of diabetic pancreatic cancer patients diabetes was new-onset. Diabetes was new-onset in 23.3% of females compared to 38.1% of males ; . The overall prevalence of diabetes was significantly higher among female pancreatic cancer patients 25% versus 43.9%; , , while diabetes prevalence was equally represented in the control group patients 22.1% versus 17.2%; , . Conclusion. The prevalence of diabetes mellitus in study group of pancreatic cancer patients was significantly higher when compared to control group. Pancreatic cancer patients with diabetes were predominantly females, while diabetes was equally prevalent among sexes in the control group. Therefore, patient sex may play important role in the risk stratification.





Author: Jan Trna, Petr Dítĕ, Arona Adamcová, Brianna J. Crawford, and Markéta Hermanová

Source: https://www.hindawi.com/



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