Distribution of ABO Blood Group and Major Cardiovascular Risk Factors with Coronary Heart DiseaseReport as inadecuate




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BioMed Research InternationalVolume 2013 2013, Article ID 782941, 5 pages

Research Article

Division of Molecular Medicine, Bose Institute, P-1-12 CIT Scheme VIIM, Kolkata 700054, India

Department of Cardiology, N.R.S. Medical College & Hospital, 138 A.J.C. Bose Road, Kolkata 700014, India

Received 24 April 2013; Revised 11 July 2013; Accepted 17 July 2013

Academic Editor: Sudhish Mishra

Copyright © 2013 Santanu Biswas et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The purpose of this study is to establish whether ABO blood group is related to coronary heart disease in an individual in Asian Indian Bengali population of eastern part of India. Two hundred and fifty 250 CHD patients and two hundred and fifty 250 age and sex matched healthy subjects were enrolled in the study. ABO blood group distribution in patients was compared with control group. Frequency of major cardiac risk factors was determined to find any correlation between blood groups and cardiovascular risk factors. The distribution of ABO blood groups in patients versus control group was A in 24.00 versus 21.60%, B in 30.80 versus 32.40%, O in 38.40 versus 21.60%, and AB in 6.80 versus 24.40%. The analysis showed significant difference in frequency of O OR = 1.857, 95%CI = 1.112–3.100, and AB OR = 0.447, 95%CI = 0.227–0.882, blood group between healthy controls and CHD individuals. Our results may suggest that the AB blood group decreases the risk of CHD in healthy controls, and it might be due to the higher concentration of high density lipoprotein cholesterol HDL-c, while the O blood group increases the risk of CHD due to lower HDL-c levels in Bengali population of eastern part of India.





Author: Santanu Biswas, Pradip K. Ghoshal, Bhubaneswar Halder, and Nripendranath Mandal

Source: https://www.hindawi.com/



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