Validation of the short version of the 10-66 dementia diagnosis in multiethnic Asian older adults in SingaporeReport as inadecuate




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BMC Geriatrics

, 17:94

Psychology, psychiatry and quality of life

Abstract

BackgroundTo validate the short version of the 10-66 dementia diagnosis against the standard version of the 10-66 dementia diagnosis and clinical diagnosis and examine concurrent validity with the World Health Organisation Disability Assessment schedule and care needs in a multiethnic Asian older adult population in Singapore.

MethodsData from the Well-being of the Singapore Elderly study, a nationally representative survey of the older Singapore Resident population aged 60 years and above was used. The validity of the short version of the 10-66 dementia diagnostic criteria derived from the Community Screening Instrument for Dementia, the modified Consortium to Establish a Registry of Alzheimer’s Disease 10-word list delayed recall and the EURO-D depression screen were examined against the standard version of the 10-66 dementia diagnosis and clinician diagnosis as a gold standard. Concurrent validity was tested by examining the relationships between the short version 10-66 dementia diagnosis, disability and care needs.

ResultsA total of 2373 respondents who had completed data on the short version diagnosis were included in this study. The majority 82.63% of respondents were of Chinese descent, 9.86% were Malays, 6.12% were of Indian descent and 1.39% belonged to other ethnic group. We found the short version 10-66 dementia diagnosis showed almost perfect agreement with the standard version 10-66 dementia diagnosis kappa = 0.90, AUC = 0.96 and substantial agreement with clinical diagnosis kappa = 0.70, AUC = 0.87. The weighted prevalence of dementia in the population was slightly higher based on the short version diagnosis than the standard version diagnosis 10.74% vs. 10.04%. We also found that those with the short version 10-66 dementia were significantly associated with higher disability β = 28.90, 95% CI = 23.62, 9.62 and needed care occasionally OR =35.21, 95% CI = 18.08, 68.59 or much of the time OR = 9.02, 95% CI = 5.21, 15.61.

ConclusionsThe study found that the short version 10-66 dementia diagnosis has excellent validity to diagnose dementia in a multiethnic Asian population in Singapore. Further research is required to determine the usefulness of this diagnosis in clinical practice or institutional settings to aid early detection and intervention for dementia.

Keywords10-66 dementia Validity Concurrent validity Older adults Dementia Asian AbbreviationsCERADConsortium to Establish a Registry of Alzheimer’s Disease CERAD

CSI-DCommunity Screening Instrument for Dementia

DSM-4Diagnostic and Statistical Manual, Fourth Edition

EURO-DEuropean Depression Scale

GMS-AGECATGeriatric Mental State-Automated Geriatric Examination for Computer Assisted Taxonomy

WHODASWorld Health Organisation Disability Assessment schedule





Author: Edimansyah Abdin - Janhavi Ajit Vaingankar - Louisa Picco - Boon Yiang Chua - Martin Prince - Siow Ann Chong - Mythily S

Source: https://link.springer.com/







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