Layperson-Oriented versus Clinical-Based Models for Assessing 10-Year Incidence of Coronary Heart Disease: National FINRISK StudyReport as inadecuate




Layperson-Oriented versus Clinical-Based Models for Assessing 10-Year Incidence of Coronary Heart Disease: National FINRISK Study - Download this document for free, or read online. Document in PDF available to download.

International Journal of Vascular MedicineVolume 2011 2011, Article ID 823782, 9 pages

Research Article

Department of Public Health, University of Helsinki, PL41 Mannerheimintie 172, 00014 Helsinki, Finland

Department of Chronic Disease Prevention, National Institute for Health and Welfare, P.O. Box 30, 00271 Helsinki, Finland

Received 28 January 2011; Accepted 9 August 2011

Academic Editor: Robert M. Schainfeld

Copyright © 2011 Qing Qiao et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

One laboratory-based and two non-laboratory-based models with and without blood pressure measures are developed based on data of 14815 men and 16617 women aged 25–64 years. During the followup 1134 men and 566 women developed coronary heart disease CHD. The area under the receiver operating characteristic curve 95% CI for prediction of CHD incidence was 0.823 0.807–0.839 for the laboratory-based model, 0.808 0.791–0.824 and 0.803 0.787–0.820 for the non-laboratory-based models with and without systolic blood pressure in men for overall comparison, and 0.878 0.856–0.901, 0.871 0.848–0.894, and 0.864 0.840–0.887, respectively, in women . The predicted rates matched well with the observed ones . Compared with the model without blood pressure, the non-laboratory-based model with blood pressure tended to reclassify individuals into the higher risk categories for both event and nonevent groups in both genders. The study concludes the predictive property of the non-laboratory-based models are good.





Author: Qing Qiao, Tiina Laatikainen, Weiguo Gao, Janne Pitkäniemi, and Erkki Vartiainen

Source: https://www.hindawi.com/



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