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Abstract: A scaling analysis is presented of the statistics of long DNA confined innanochannels and nanoslits. It is argued that there are several regimes inbetween the de Gennes and Odijk limits introduced long ago. The DNA chain foldsback on itself giving rise to a global persistence length which may be verylarge owing to entropic deflection. Moreover, there is an orientationalexcluded-volume effect between the DNA segments imposed solely by thenanoconfinement. These two effects cause the chain statistics to be intricateleading to nontrivial power laws for the chain extension in the intermediateregimes. It is stressed that DNA confinement within nanochannels differs fromthat in nanoslits because the respective orientational excluded-volume effectsare not the same.



Author: T. Odijk

Source: https://arxiv.org/







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