Conditional Granger Causality Analysis of Effective Connectivity during Motor Imagery and Motor Execution in Stroke PatientsReport as inadecuate




Conditional Granger Causality Analysis of Effective Connectivity during Motor Imagery and Motor Execution in Stroke Patients - Download this document for free, or read online. Document in PDF available to download.

BioMed Research International - Volume 2016 2016, Article ID 3870863, 9 pages -

Research Article

Department of Medical Image, College of Biomedical Engineering, Third Military Medical University, No. 30, Gaotanyan Street, Shapingba District, Chongqing 400038, China

Department of Rehabilitation, Southwest Hospital, Third Military Medical University, No. 30, Gaotanyan Street, Shapingba District, Chongqing 400038, China

Received 22 December 2015; Revised 1 March 2016; Accepted 10 March 2016

Academic Editor: Eiji Kirino

Copyright © 2016 Li Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Aims. Motor imagery has emerged as a promising technique for the improvement of motor function following stroke, but the mechanism of functional network reorganization in patients during this process remains unclear. The aim of this study is to evaluate the cortical motor network patterns of effective connectivity in stroke patients. Methods. Ten stroke patients with right hand hemiplegia and ten normal control subjects were recruited. We applied conditional Granger causality analysis CGCA to explore and compare the functional connectivity between motor execution and motor imagery. Results. Compared with the normal controls, the patient group showed lower effective connectivity to the primary motor cortex M1, the premotor cortex PMC, and the supplementary motor area SMA in the damaged hemisphere but stronger effective connectivity to the ipsilesional PMC and M1 in the intact hemisphere during motor execution. There were tighter connections in the cortical motor network in the patients than in the controls during motor imagery, and the patients showed more effective connectivity in the intact hemisphere. Conclusions. The increase in effective connectivity suggests that motor imagery enhances core corticocortical interactions, promotes internal interaction in damaged hemispheres in stroke patients, and may facilitate recovery of motor function.





Author: Li Wang, Jingna Zhang, Ye Zhang, Rubing Yan, Hongliang Liu, and Mingguo Qiu

Source: https://www.hindawi.com/



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