Zika Virus, Chikungunya Virus, and Dengue Virus in Cerebrospinal Fluid from Adults with Neurological Manifestations, Guayaquil, EcuadorReport as inadecuate




Zika Virus, Chikungunya Virus, and Dengue Virus in Cerebrospinal Fluid from Adults with Neurological Manifestations, Guayaquil, Ecuador - Download this document for free, or read online. Document in PDF available to download.

Journal Title:

Frontiers in Microbiology

Volume:

Volume 8, Number 42

Publisher:

Frontiers Media | 2017-01-24

Type of Work:

Article | Final Publisher PDF

Abstract: Zika virus ZIKV, chikungunya virus CHIKV, and dengue virus DENV have been associated with clinical presentations that involve acute neurological complaints. In the current study, we identified ZIKV, CHIKV, and DENV in cerebrospinal fluid CSF samples from patients admitted to the Hospital Luis Vernaza Guayaquil, Ecuador to the Emergency Room or the Intensive Care Unit, with neurological symptoms and-or concern for acute arboviral infections. Viral RNA from one or more virus was detected in 12-16 patients. Six patients were diagnosed with meningitis or encephalitis, three with Guillain–Barré Syndrome, and one with CNS vasculitis. Two additional patients had a systemic febrile illness including headache that prompted testing of CSF. Two patients, who were diagnosed with encephalitis and meningoencephalitis, died during their hospitalizations. These cases demonstrate the breadth and significance of neurological manifestations associated with ZIKV, CHIKV, and DENV infections.

Keywords: Zika virus - Guillain-Barré syndrome - Meningitis - Chikungunya virus - Dengue virus - Cerebrospinal fluid - Molecular diagnosis -



Author: Nathalie Acevedo, Jesse Waggoner, Michelle Rodriguez, Lissette Rivera, José Landivar, Benjamin Pinsky, Hector Zambrano,

Source: https://open.library.emory.edu/



DOWNLOAD PDF




Related documents