Navigated Transcranial Magnetic Stimulation: A Biologically Based Assay of Lower Extremity Impairment and Gait VelocityReport as inadecuate




Navigated Transcranial Magnetic Stimulation: A Biologically Based Assay of Lower Extremity Impairment and Gait Velocity - Download this document for free, or read online. Document in PDF available to download.

Journal Title:

Neural Plasticity

Volume:

Volume 2017

Publisher:

Hindawi Publishing Corporation | 2017-01-01, Pages 6971206-6971206

Type of Work:

Article | Final Publisher PDF

Abstract: Objectives: a To determine associations among motor evoked potential MEP amplitude, MEP latency, lower extremity LE impairment, and gait velocity and b determine the association between the presence of a detectable MEP signal with LE impairment and with gait velocity. Method: 35 subjects with chronic, stable LE hemiparesis were undergone TMS, the LE section of the Fugl-Meyer Impairment Scale LE FM, and 10-meter walk test. We recorded presence, amplitude, and latency of MEPs in the affected tibialis anterior TA and soleus SO. Results: MEP presence was associated with higher LEFM scores in both the TA and SO. MEP latency was larger in subjects with lower LEFM and difficulty walking. Conclusion: MEP latency appears to be an indicator of LE impairment and gait. Significance. Our results support the precept of using TMS, particularly MEP latency, as an adjunctive LE outcome measurement and prognostic technique.

Subjects: Biology, Neuroscience - Health Sciences, Medicine and Surgery - Health Sciences, Rehabilitation and Therapy - Research Funding: This work was supported by grants from Nexstim, Ltd., the Drake Center Foundation, and the National Institutes of Health R01AT004454-04; R03 HD062545-02.





Author: Heather T. Peters, Kari Dunning, Samir Belagaje, Brett M. Kissela, Jun Ying, Jarmo Laine, Stephen J. Page,

Source: https://open.library.emory.edu/



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