Noninvasive positive pressure ventilation enhances the effects of aerobic training on cardiopulmonary functionReport as inadecuate




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Purpose

The purpose of this study was to determine the effect of aerobic training under noninvasive positive pressure ventilation NPPV on maximal oxygen uptake .

Methods

Ten healthy young male volunteers participated in the study. Before the training, stroke volume SV and cardiac output CO were measured in all subjects under 0, 4, 8, and 12 cmH2O NPPV at rest. Then, the subjects exercised on a cycle ergometer at 60% of pre-training for 30 min daily for 5 consecutive days with-without NPPV. The 5-day exercise protocol was repeated after a three-week washout period without-with NPPV. The primary endpoint was changes in . The secondary endpoints were changes in SV, CO, maximum heart rate HRmax, maximum respiratory rate RRmax, maximum expiratory minute volume VEmax and the percent change in plasma volume PV.

Results

NPPV at 12 cmH2O significantly reduced SV and CO at rest. significantly increased after 5 days training with and without NPPV, but the magnitude of increase in after training under 12 cmH2O NPPV was significantly higher than after training without NPPV. VEmax significantly increased after training under NPPV, but not after training without NPPV. HRmax and RRmax did not change during training irrespective of NPPV. The percent change in PV was similar between training with and without NPPV. The 5-day training program with NPPV resulted in greater improvement in than without NPPV.

Conclusions

Aerobic training under NPPV has add-on effects on and exercise-related health benefits in healthy young men.



Author: Takashi Moriki, Takeshi Nakamura , Yoshi-ichiro Kamijo, Yukihide Nishimura, Motohiko Banno, Tokio Kinoshita, Hiroyasu Uenishi, Fu

Source: http://plos.srce.hr/



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