Bundled-Optode Method in Functional Near-Infrared SpectroscopyReport as inadecuate

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In this paper, a theory for detection of the absolute concentrations of oxy-hemoglobin HbO and deoxy-hemoglobin HbR from hemodynamic responses using a bundled-optode configuration in functional near-infrared spectroscopy fNIRS is proposed. The proposed method is then applied to the identification of two fingers i.e., little and thumb during their flexion and extension. This experiment involves a continuous-wave-type dual-wavelength 760 and 830 nm fNIRS and five healthy male subjects. The active brain locations of two finger movements are identified based on the analysis of the t- and p-values of the averaged HbOs, which are quite distinctive. Our experimental results, furthermore, revealed that the hemodynamic responses of two-finger movements are different: The mean, peak, and time-to-peak of little finger movements are higher than those of thumb movements. It is noteworthy that the developed method can be extended to 3-dimensional fNIRS imaging.

Author: Hoang-Dung Nguyen, Keum-Shik Hong , Yong-Il Shin

Source: http://plos.srce.hr/


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