Tuberculosis Case Finding in Benin, 2000–2014 and Beyond: A Retrospective Cohort and Time Series StudyReport as inadecuate

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Tuberculosis Research and Treatment - Volume 2016 2016, Article ID 3205843, 9 pages -

Research Article

Programme National contre la Tuberculose, 01 BP 321 Cotonou, Benin

Faculté de Médecine, Université de Parakou, Parakou, Benin

International Union against Tuberculosis and Lung Disease, Paris, France

London School of Hygiene and Tropical Medicine, London, UK

Received 31 December 2015; Revised 18 April 2016; Accepted 21 April 2016

Academic Editor: Sarman Singh

Copyright © 2016 Serge Ade et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objective. To determine any changes in tuberculosis epidemiology in the last 15 years in Benin, seasonal variations, and forecasted numbers of tuberculosis cases in the next five years. Materials and Methods. Retrospective cohort and time series study of all tuberculosis cases notified between 2000 and 2014. The -R- software version 3.2.1 Institute for Statistics and Mathematics Vienna Austria and the Box-Jenkins 1976 modeling approach were used for time series analysis. Results. Of 246943 presumptive cases, 54303 22% were diagnosed with tuberculosis. Annual notified case numbers increased, with the highest reported in 2011. New pulmonary bacteriologically confirmed tuberculosis NPBCT represented 78%  ± SD 2%. Retreatment cases decreased from 10% to 6% and new pulmonary clinically diagnosed cases increased from 2% to 8%. NPBCT notification rates decreased in males from 2012, in young people aged 15–34 years and in Borgou-Alibori region. There was a seasonal pattern in tuberculosis cases. Over 90% of NPBCT were HIV-tested with a stable HIV prevalence of 13%. The ARIMA best fit model predicted a decrease in tuberculosis cases finding in the next five years. Conclusion. Tuberculosis case notifications are predicted to decrease in the next five years if current passive case finding is used. Additional strategies are needed in the country.

Author: Serge Ade, Wilfried Békou, Mênonli Adjobimey, Omer Adjibode, Gabriel Ade, Anthony D. Harries, and Séverin Anagonou



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