Health Professionals Knowledge, Attitudes and Practices about Pharmacovigilance in India: A Systematic Review and Meta-AnalysisReport as inadecuate




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Background

Spontaneous or voluntary reporting of suspected adverse drug reactions ADRs is one of the vital roles of all health professionals. In India, under-reporting of ADRs by health professionals is recognized as one of the leading causes of poor ADR signal detection. Therefore, reviewing the literature can provide a better understanding of the status of knowledge, attitude and practice KAP of Pharmacovigilance PV activities by health professionals.

Methods

A systematic review was performed through Pubmed, Scopus, Embase and Google Scholar scientific databases. Studies pertaining to KAP of PV and ADR reporting by Indian health professionals between January 2011 and July 2015 were included in a meta-analysis.

Results

A total of 28 studies were included in the systematic review and 18 of them were selected for meta-analysis. Overall, 55.6% 95% CI 44.4–66.9; p<0.001 of the population studied were not aware of the existence of the Pharmacovigilance Programme in India PvPI, and 31.9% 95% CI 16.3–47.4; p<0.001 thought that -all drugs available in the market are safe-. Furthermore, 28.7% 95% CI 16.4–40.9; p<0.001 of them were not interested in reporting ADRs and 74.5%, 95% CI 67.9–81.9; p<0.001 never reported any ADR to PV centers.

Conclusion

There was an enormous gap of KAP towards PV and ADR reporting, particularly PV practice in India. There is therefore an urgent need for educational awareness, simplification of the ADR reporting process, and implementation of imperative measures to practice PV among healthcare professionals. In order to understand the PV status, PvPI should procedurally assess the KAP of health professionals PV activities in India.



Author: Akshaya Srikanth Bhagavathula , Asim Ahmed Elnour, Shazia Qasim Jamshed, Abdulla Shehab

Source: http://plos.srce.hr/



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