Successful Treatment with Clonazepam and Pramipexole of a Patient with Sleep-Related Eating Disorder Associated with Restless Legs Syndrome: A Case ReportReport as inadecuate




Successful Treatment with Clonazepam and Pramipexole of a Patient with Sleep-Related Eating Disorder Associated with Restless Legs Syndrome: A Case Report - Download this document for free, or read online. Document in PDF available to download.

Case Reports in MedicineVolume 2012 2012, Article ID 893681, 4 pages

Case Report

Department of Psychosomatic Medicine, Takano Hospital, 4-2-88 Obiyama, Kumamoto 862-0924, Japan

Oyama Medical Clinic, 6-10-15 Oyama, Kumamoto 861-8045, Japan

Coloproctology Center, Takano Hospital, 4-2-88 Obiyama, Kumamoto 862-0924, Japan

Received 20 November 2011; Accepted 22 December 2011

Academic Editor: Linda Gonder-Frederick

Copyright © 2012 Nobuyuki Kobayashi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Sleep-related eating disorder SRED is characterized by recurrent episodes of involuntary eating during sleep period and is often associated with restless legs syndrome RLS. Although pharmacotherapy is recommended for SRED patients, no drug have shown promising effects so far. The patient, a 48-year-old Japanese housewife, first visited our clinic and complained about nighttime eating. She had a history of hypertension, diabetes mellitus, sleep apnea syndrome, and depression. Insomnia appeared 10 years before the first visit and she often received hypnosedatives; at the same time, she developed nocturnal eating episodes. She had amnesia for these episodes, and she felt urge to move her legs while sleeping. The patient was diagnosed with SRED and RLS. Reduction in the doses of triazolam decreased her nighttime eating frequency, and her complete amnesia changed to vague recall of eating during night. Clonazepam 1.0 mg at bedtime decreased nocturnal eating frequency from 1 to 2 times per month, though sleepwalking remained. Administration of pramipexole 0.125 mg relieved all symptoms including SRED, RLS, and sleepwalking. This is the first paper to report that the combination of clonazepam and pramipexole therapy-reduced SRED episodes and RLS symptoms.





Author: Nobuyuki Kobayashi, Ryohei Yoshimura, and Masahiro Takano

Source: https://www.hindawi.com/



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