Antepartum Membrane Stripping in GBS Carriers, Is It Safe The STRIP-G StudyReport as inadecuate




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Objective

Stripping of the membranes is an established and widely utilized obstetric procedure associated with higher spontaneous vaginal delivery rates, reduced need for formal induction of labor and a lower likelihood of post-term pregnancy. Due to the theoretical concern of bacterial seeding during the procedure many practitioners choose not to sweep the membranes in Group B Streptococcus GBS colonized patients. We conducted ‘the STRIP-G study’ in order to determine whether maternal and neonatal outcomes are affected by GBS carrier status in women undergoing membrane stripping.

Study design

We conducted a prospective study in a tertiary referral center, comparing maternal and neonatal outcomes following membrane stripping among GBS-positive, GBS-negative, and GBS-unknown patients. We compared the incidence of composite adverse neonatal outcomes primary outcome among the three study groups, while secondary outcome measure was composite adverse maternal outcomes.

Results

A total of 542 women were included in the study, of which 135 were GBS-positive, 361 GBS-negative, and 46 GBS-unknown status. Demographic, obstetric, and intra-partum characteristics were similar for all groups. Adverse neonatal outcomes were observed in 8 5.9%, 31 8.6%, and 2 4.3% in the GBS-positive, GBS-negative, and unknown groups, respectively P = 0.530, Odds Ratio between GBS-Positive vs. GBS-Negative groups 0.67 95%, CI = 0.30–1.50; while composite adverse maternal outcomes occurred in 9 6.66%, 31 8.59%, and 5 10.87% in the GBS-positive, GBS-negative, and unknown groups, respectively P = 0.617.

Conclusions

Antepartum membrane stripping in GBS carriers appears to be a safe obstetrical procedure that does not adversely affect maternal or neonatal outcomes.



Author: Doron Kabiri , Yael Hants, Tom Raz Yarkoni, Esther Shaulof, Smadar Eventov Friedman, Ora Paltiel, Ran Nir-Paz, Wesam E. Aljamal,

Source: http://plos.srce.hr/



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