Fat Modulates the Relationship between Sarcopenia and Physical Function in Nonobese Older AdultsReport as inadecuate




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Current Gerontology and Geriatrics ResearchVolume 2012 2012, Article ID 216185, 6 pages

Research Article

Department of Physical Therapy, University of Utah, Salt Lake City, UT 84108, USA

Department of Pharmacotherapy, University of Utah, Salt Lake City, UT 84108, USA

Received 1 June 2011; Revised 20 September 2011; Accepted 13 October 2011

Academic Editor: D. Taaffe

Copyright © 2012 Robin L. Marcus et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

It is intuitive to think that sarcopenia should be associated with declines in physical function though recent evidence questions this assertion. This study investigated the relationship between absolute and relative sarcopenia, with physical performance in 202 nonobese mean BMI  kg-ht

community-dwelling older mean age = years adults. While absolute sarcopenia appendicular skeletal mass ASM-ht

was either not associated, or weakly associated with physical performance, relative sarcopenia ASM-kg demonstrated moderate to , relationships with performance outcomes in both males and females. Knee extension strength and leg extension power were both related to absolute sarcopenia in females and not in males. Strength and power were associated with relative sarcopenia in both sexes from to   . The ratio of lean mass to total body mass, that is, relative sarcopenia, is an important consideration relative to physical function in older adults even in the absence of obesity. Stratifying these individuals into equal tertiles of total body fat revealed a trend of diminished regression coefficients across each incrementally higher fat grouping for performance measures, providing further evidence that total body fat modulates the relationship between sarcopenia and physical function.





Author: Robin L. Marcus, Diana I. Brixner, Sameer Ghate, and Paul LaStayo

Source: https://www.hindawi.com/



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