Disability Pension at the Time of Coronary Revascularisation Is Associated with Higher Five-Year Mortality; A Swedish Nationwide, Register-Based Prospective Cohort StudyReport as inadecuate




Disability Pension at the Time of Coronary Revascularisation Is Associated with Higher Five-Year Mortality; A Swedish Nationwide, Register-Based Prospective Cohort Study - Download this document for free, or read online. Document in PDF available to download.

Background

Although coronary revascularisation by coronary artery bypass grafting CABG and percutaneous coronary intervention PCI are common procedures, little is known regarding disability pension DP at the time of coronary revascularisation and its association with mortality. The aim was to investigate the five-year mortality following a first coronary revascularisation among women and men on DP, compared with those not on DP at the time of intervention, accounting for socio-demographic and medical factors.

Material and Methods

A nationwide prospective population-based cohort study was conducted, using national registers including 70,040 patients 80% men, aged 30–64 years, with a first CABG n = 24,987; 36% or PCI n = 45,053; 64% during 1994–2006 in Sweden, who were alive 30 days after the intervention. The main outcome was all-cause and cause-specific mortality within five years or through 31 December 2006, following CABG and PCI, and the exposure was DP at the time of a first coronary revascularisation. Information on DP, patient characteristics, date and cause of death was obtained from nationwide registers. Hazard ratios HR with 95% confidence intervals CI for the outcome were estimated, using Cox proportional hazard regression analyses. All analyses were stratified by type of intervention and gender.

Findings

Four percent died following coronary revascularisation. Cardiovascular disease was the most common cause of death 54%, followed by neoplasms 25%. Regardless of type of intervention, gender and after multivariable adjustments, patients on DP had a higher HR for five-year mortality compared with those not on DP at time of revascularisation CABG: women HR 2.14; 95% CI 1.59–2.89, men HR 2.09; 1.84–2.38, PCI: women HR 2.25; 1.78–2.83, men HR 1.95; 1.72–2.21. Young women on DP at the time of PCI had a substantially higher HR HR 4.10; 95% CI: 2.25–7.48.

Conclusion

Patients on DP at the time of first coronary revascularisation had a higher five-year risk of mortality compared with those not on DP.



Author: Katharina Zetterström , Margaretha Voss, Kristina Alexanderson, Torbjörn Ivert, Kenneth Pehrsson, Niklas Hammar, Marjan Vaez

Source: http://plos.srce.hr/



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