Effect of Paralysis at the Time of ProSeal Laryngeal Mask Airway Insertion on Pharyngolaryngeal Morbidities. A Randomized TrialReport as inadecuate




Effect of Paralysis at the Time of ProSeal Laryngeal Mask Airway Insertion on Pharyngolaryngeal Morbidities. A Randomized Trial - Download this document for free, or read online. Document in PDF available to download.

Neuromuscular block results in the loss of muscular tone in the upper airway, which might contribute to the increased postoperative airway morbidity followed by ProSeal laryngeal mask airway PLMA insertion. We compared the pharyngolaryngeal discomfort exerted by the PLMA according to the neuromuscular block. One hundred sixty patients undergoing surgery for breast disease or inguinal hernia were anesthetized with propofol and remifentanil by target controlled infusion. Rocuronium 0.6 mg-kg NMBA group, n = 80 or normal saline No-NMBA group, n = 80 was administered after the loss of consciousness, and one anesthesiologist inserted the PLMA. Postoperative pharyngolaryngeal discomfort was evaluated at postoperative 1 h. Traumatic event was recorded based on the blood trace on the surface of the PLMA cuff. Insertion time, insertion attempt number, sealing pressure, and fiberoptic brochoscopic grades were evaluated. Patients’ characteristics and the PLMA insertion condition insertion time, successful insertion attempt number, fiberoptic bronchoscopic grade, and sealing pressure were similar between the two groups. The PLMA can be successfully inserted in non-paralyzed patients with less postoperative pharyngolaryngeal discomfort than when a neuromuscular blocking agent is used 13.8% vs. 30.0%, P = 0.021. The incidence of traumatic events is also reduced when no neuromuscular blocking agent is used 16.3% vs. 32.5%, P = 0.026. Regardless of whether or not a surgical procedure requires muscular relaxation, there is no need to administer neuromuscular blocking agents solely for the purpose of PLMA insertion.

Trial Registration

ClinicalTrials.gov NCT01035021



Author: Hyo-Seok Na , Young-Tae Jeon , Hyun-Jung Shin, Ah-Young Oh, Hee-Pyoung Park, Jung-Won Hwang

Source: http://plos.srce.hr/



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