Adverse Outcomes after Non-Chest Surgeries in Patients with Pulmonary Tuberculosis: A Nationwide StudyReport as inadecuate




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Background

The association between pulmonary tuberculosis TB and postoperative outcomes remains unknown. This study investigated outcomes following non-chest surgeries in patients with previous pulmonary TB.

Methods

Using Taiwan’s National Health Insurance Research Database, we analyzed 6911 patients aged ≥ 20 years with preoperative diagnosis of pulmonary TB and 6911 propensity score-matched controls receiving non-chest surgeries in 2008–2010. Postoperative outcomes were compared between patients with or without pulmonary TB by calculating adjusted odds ratios ORs and 95% confidence intervals CIs in the multivariate logistic regressions.

Results

Surgical patients with pulmonary TB had a significantly higher postoperative complication rates than controls, including septicemia, pneumonia, acute renal failure, deep wound infection, overall complications, and 30-day postoperative mortality OR 1.41; 95% CI 1.07–1.86. The ORs of patients with low-income status were as high as 2.27 95% CI 1.03–5.03. Preoperative use of TB drugs and TB-related medical expenditure also associated with higher postoperative mortality among surgical patients with pulmonary TB.

Conclusions

Surgical patients with pulmonary TB have significantly increased risks of postoperative complications and mortality after non-chest surgeries. This study suggests the need to improve postoperative care for surgical patients with pulmonary TB.



Author: Chi-Chen Ke , Chao-Shun Lin, Chun-Chieh Yeh, Chi-Li Chung, Chih-Jen Hung, Chien-Chang Liao , Ta-Liang Chen

Source: http://plos.srce.hr/



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