Sprint Interval and Sprint Continuous Training Increases Circulating CD34 Cells and Cardio-Respiratory Fitness in Young Healthy WomenReport as inadecuate




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Introduction

The improvement of vascular health in the exercising limb can be attained by sprint interval training SIT. However, the effects on systemic vascular function and on circulating angiogenic cells CACs which may contribute to endothelial repair have not been investigated. Additionally, a comparison between SIT and sprint continuous training SCT which is less time committing has not been made.

Methods

12 women 22±2 yrs completed 12 sessions of either SIT n = 6 or work-matched SCT n = 6 on 3 days-week. Pre and post-training assessments included brachial artery endothelial function and peripheral blood analysis for CAC number CD34+-CD34+CD45dim. CAC function was measured by migration and adhesion assays. Cardio-respiratory fitness, carotid arterial stiffness and carotid-radial and brachial-foot pulse wave velocity PWV were also evaluated.

Results

CD34+ CACs increased following training in both groups but CD34+CD45dim did not Pre CD34+: 40±21-105 leukocytes, Post CD34+: 56±24-105 leukocytes, main time effect p<0.05. Brachial artery flow-mediated dilation FMD increased following SIT but SCT had no effect Pre SIT: 5.0±3.4%, Post SIT: 5.9±3.0%, Pre SCT: 7.2±2.7%, Post SCT: 6.5±2.9%; group x time interaction p = 0.08. increased in both training groups Pre: 34.6±4.6 ml•kg•ml−1, Post: 36.9±5.4 ml•kg•ml−1, main time effect p<0.05. CAC function, carotid arterial stiffness and PWV did not change after training p>0.05.

Discussion

SCT involving little time commitment is comparable to SIT in increasing CD34+ cell number and . An increased mobilisation of CD34+ CACs suggests that sprint training may be an effective method to enhance vascular repair.



Author: Emma Harris, Mark Rakobowchuk, Karen M. Birch

Source: http://plos.srce.hr/



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