Self-Administered Tuberculosis Treatment Outcomes in a Tribal Population on the Indo-Myanmar Border, Nagaland, IndiaReport as inadecuate




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Background

Multiple strategies are being adopted by national tuberculosis TB programmes to achieve universal coverage of tuberculosis treatment. However, populations living in ‘hard-to-reach’ areas of north-east India have poor access to health services. Our study aimed to detail treatment outcomes in TB program supported by Médecins Sans Frontières MSF and using an alternative model of TB treatment delivery in Mon district, Nagaland, India.

Methods

This was a retrospective cohort study of TB patients, initiated on self-administered therapy SAT through Mon District Hospital, Nagaland, India between April 2012 and March 2013.

Results

A total of 238 tuberculosis patients had final TB treatment outcomes during the study period, including 82 and 156 from semi-urban and rural areas respectively. The majority of patients 62%, 147-238 were suffering from pulmonary, smear-positive tuberculosis. Overall, 74% of patients 175-238 had successful outcomes, being cured or having completed their treatment. Females 81%, pulmonary TB patients 75% and those on a Category I regimen 79% had better treatment success rates than males 67%, extra-pulmonary TB patients 62% and patients on a Category II regimen 61%. The univariate and bivariate analyses found age, sex and TB treatment regimen significantly associated with unsuccessful TB treatment outcomes defined as death, loss-to-follow-up and failure. However, only older age showed significance in a multivariate binary logistic regression model.

Conclusion

Our study suggests that self-administered TB treatment is feasible for patients living in areas with limited or no access to health services. The relatively low number of patients with adverse outcomes suggests that SAT models are safe; other advantages include the need for fewer resources and less frequent movements by patients. National TB programmes should consider allowing SAT strategies for delivery of TB treatment to ‘hard-to-reach’ populations, which could in turn help to achieve universal coverage and contribute to global TB elimination by 2050.



Author: Mrinalini Das , Petros Isaakidis, Rahul Shenoy, Rey Anicete, Hemant Kumar Sharma, Imyangluba Ao, Kaikho Osah, Homa Mansoor, Peter

Source: http://plos.srce.hr/



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