Analysis of the Retinal Nerve Fiber Layer in Retinitis Pigmentosa Using Optic Coherence TomographyReport as inadecuate




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Journal of Ophthalmology - Volume 2015 2015, Article ID 157365, 5 pages -

Research Article

Department of Ophthalmology, Bahcelievler State Hospital, 34180 Istanbul, Turkey

Department of Ophthalmology, Okmeydanı Education and Research Hospital, 34384 Istanbul, Turkey

Department of Ophthalmology, Dumlupinar University School of Medicine, 43270 Kutahya, Turkey

Department of Ophthalmology, Mus State Hospital, 49000 Mus, Turkey

Received 28 April 2015; Revised 23 June 2015; Accepted 5 July 2015

Academic Editor: Suphi Taneri

Copyright © 2015 Medine Aslı Yıldırım et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Aim. To evaluate the peripapillary retinal nerve fiber layer RNFL changes in retinitis pigmentosa RP patients using spectral domain optic coherence tomography Sd-OCT. Methods. We retrospectively examined medical records of forty-four eyes of twenty-two RP patients. The results were also compared with those of previously reported forty-four eyes of twenty-two normal subjects controls. Records of average and four quadrants peripapillary RNFL thickness measurements using Sd-OCT were assessed. Results. In RP patients the mean RNFL thickness was 97.57 ± 3.21 μm. The RNFL in the superior, temporal, nasal, and inferior quadrants was 119.18 ± 4.47 μm, 84.68 ± 2.31 μm, 75.09 ± 3.34 μm, and 113.88 ± 4.25 μm, respectively. While the thinning of RNFL was predominantly observed in the inferior quadrant, the thickening was mostly noted in temporal quadrant. The differences between mean, superior, and nasal quadrant RNFL thicknesses were not statistically significant when compared with control group. The RP patients had thinner inferior quadrant and thicker temporal quadrant than control group . Conclusion. Sd-OCT is highly sensitive and effective instrument to detect RNFL changes in RP patients. RNFL measurements can provide information about the progression of retinitis pigmentosa and may provide prognostic indices for future treatment modalities.





Author: Medine Aslı Yıldırım, Burak Erden, Mehmet Tetikoğlu, Özlem Kuru, and Mustafa Elçioğlu

Source: https://www.hindawi.com/



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