Prevalence of Dyslipidemia in Urban and Rural India: The ICMR–INDIAB StudyReport as inadecuate




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Aim

To study the pattern and prevalence of dyslipidemia in a large representative sample of four selected regions in India.

Methods

Phase I of the Indian Council of Medical Research–India Diabetes ICMR-INDIAB study was conducted in a representative population of three states of India Tamil Nadu, Maharashtra and Jharkhand and one Union Territory Chandigarh, and covered a population of 213 million people using stratified multistage sampling design to recruit individuals ≥20 years of age. All the study subjects n = 16,607 underwent anthropometric measurements and oral glucose tolerance tests were done using capillary blood except in self-reported diabetes. In addition, in every 5th subject n = 2042, a fasting venous sample was collected and assayed for lipids. Dyslipidemia was diagnosed using National Cholesterol Education Programme NCEP guidelines.

Results

Of the subjects studied, 13.9% had hypercholesterolemia, 29.5% had hypertriglyceridemia, 72.3% had low HDL-C, 11.8% had high LDL-C levels and 79% had abnormalities in one of the lipid parameters. Regional disparity exists with the highest rates of hypercholesterolemia observed in Tamilnadu 18.3%, highest rates of hypertriglyceridemia in Chandigarh 38.6%, highest rates of low HDL-C in Jharkhand 76.8% and highest rates of high LDL-C in Tamilnadu 15.8%. Except for low HDL-C and in the state of Maharashtra, in all other states, urban residents had the highest prevalence of lipid abnormalities compared to rural residents. Low HDL-C was the most common lipid abnormality 72.3% in all the four regions studied; in 44.9% of subjects, it was present as an isolated abnormality. Common significant risk factors for dyslipidemia included obesity, diabetes, and dysglycemia.

Conclusion

The prevalence of dyslipidemia is very high in India, which calls for urgent lifestyle intervention strategies to prevent and manage this important cardiovascular risk factor.



Author: Shashank R. Joshi, Ranjit Mohan Anjana, Mohan Deepa, Rajendra Pradeepa, Anil Bhansali, Vinay K. Dhandania, Prashant P. Joshi, Ran

Source: http://plos.srce.hr/



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