The Relation of Rapid Changes in Obesity Measures to Lipid Profile - Insights from a Nationwide Metabolic Health Survey in 444 Polish CitiesReport as inadecuate




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Objective

The impact of fast changes in obesity indices on other measures of metabolic health is poorly defined in the general population. Using the Polish accession to the European Union as a model of political and social transformation we examined how an expected rapid increase in body mass index BMI and waist circumference relates to changes in lipid profile, both at the population and personal level.

Methods

Through primary care centres in 444 Polish cities, two cross-sectional nationwide population-based surveys LIPIDOGRAM 2004 and LIPIDOGRAM 2006 examined 15,404 and 15,453 adult individuals in 2004 and 2006, respectively. A separate prospective sample of 1,840 individuals recruited in 2004 had a follow-up in 2006 LIPIDOGRAM PLUS.

Results

Two years after Polish accession to European Union, mean population BMI and waist circumference increased by 0.6% and 0.9%, respectively. This tracked with a 7.6% drop in HDL-cholesterol and a 2.1% increase in triglycerides all p<0.001 nationwide. The direction and magnitude of the population changes were replicated at the personal level in LIPIDOGRAM PLUS 0.7%, 0.3%, 8.6% and 1.8%, respectively. However, increases in BMI and waist circumference were both only weakly associated with HDL-cholesterol and triglycerides changes prospectively. The relation of BMI to the magnitude of change in both lipid fractions was comparable to that of waist circumference.

Conclusions

Moderate changes in obesity measures tracked with a significant deterioration in measures of pro-atherogenic dyslipidaemia at both personal and population level. These associations were predominantly driven by factors not measureable directly through either BMI or waist circumference.



Author: Bernhard M. Kaess, Jacek Jóźwiak, Christopher P. Nelson, Witold Lukas, Mirosław Mastej, Adam Windak, Tomasz Tomasik, Władysł

Source: http://plos.srce.hr/



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