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The global description uses composition, transition and distribution to describe an amino acid sequence and has been widely adopted in various fields. Here we integrate it with properties of nucleic acid and form a new method to digitize DNA sequence. Through this method we can use a 39-dimession vector to represent a DNA sequence. We use the exon-1 of β-Globin genes of eight species to verify this method and compare with other methods. A similar result with other method proves that this method is persuading. This method provides a new strategy to digitize DNA sequence and generates DNA sequence descriptor vector. It is different from other methods and this method only produces a 39-dimession vector and not depends on the length of DNA sequence.


DNA Sequence, Characteristic Sequence, Global Description, Digitize DNA

Cite this paper

Xu, X. and Zhu, F. 2017 A New Method to Digitize DNA Sequence. Journal of Biosciences and Medicines, 5, 7-12. doi: 10.4236-jbm.2017.53002.

Author: Xiaofei Xu, Feng Zhu*

Source: http://www.scirp.org/


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