Schizophrenia - a parameters' game - Quantitative Biology > Quantitative MethodsReport as inadecuate




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Abstract: Schizophrenia is a severe, currently incurable, relatively common mentalcondition. Its symptoms are complex and widespread. It structurally andfunctionally affects cortical and subcortical regions involved in cognitive,emotional and motivational aspects of behavior. Its cause is unknown, itsdiagnosis is based on statistical behavior and its treatment is elusive.Our paradigm addresses the complexity of schizophrenic symptoms. Buildingupon recent neural vulnerability and limbic dysregulation hypotheses, it offersa mathematical model for the evolution of the limbic system under perturbation.Dependence on parameters and the concept of -bifurcation- could be the key tounderstanding the threshold between -normality- and -disease-.



Author: Anca R. Radulescu

Source: https://arxiv.org/







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