Expression and Significance of IL-6 and bFGF in Human Tongue Squamous Cell CarcinomaReport as inadecuate




Expression and Significance of IL-6 and bFGF in Human Tongue Squamous Cell Carcinoma - Download this document for free, or read online. Document in PDF available to download.

Objective: To detect the expression and pathological significances of Interleukin-6 IL-6 and basic fibroblast growth factor bFGF in tongue squamous cell carcinoma TSCC. Methods: A tissue array was analyzed immunohistochemically. The expression levels of IL-6 and bFGF in tissues were recorded semi-quantitatively. Results: The positive expression of IL-6 in normal, benign tumor, and carcinoma groups was 12.50% ± 5.575%, 39.00% ± 1.41%, 77.26% ± 17.07% respectively, and the expression among the three groups showed significant differences P < 0.05. The expression of bFGF in benign tumor was lower than that in normal groups and squamous cell carcinoma. The positive expression was 6.50% ± 2.12%, 23.75% ± 4.79%, 42.33% ± 29.89% respectively, and the expression among the three groups showed significant differences P < 0.05. Furthermore, there were positive correlations between IL-6 and bFGF P < 0.05. Conclusion: It indicates that combining immunohistochemical examination of IL-6 and bFGF has an important reference value on the pathological diagnosis of tongue squamous cell carcinoma.

KEYWORDS

Tongue Squamous Cell Carcinoma, Il-6, bFGF, Tissue Array

Cite this paper

Hou, J. , He, Z. , Hou, X. , Liu, Y. , Zhang, W. and Duan, J. 2017 Expression and Significance of IL-6 and bFGF in Human Tongue Squamous Cell Carcinoma. Journal of Cancer Therapy, 8, 210-215. doi: 10.4236-jct.2017.82017.





Author: Ju-Hua Hou1, Zheng-Bing He2, Xiao-Ju Hou3, Yuan-Yue Liu1*, Wen-Jiang Zhang1, Juan Duan1

Source: http://www.scirp.org/



DOWNLOAD PDF




Related documents