Point-of-Care Testing Using Three Dimensional Optical Biosensor Based on Microfluidic TechnologyReport as inadecuate




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We have presented a three dimensional optical protein chip that fulfills the demanding for point-of-care diagnostics in terms of ease-of-use one step assay, miniaturization 5 μl. The artful combination of magnetic nanoparticles on chip and total internal reflection imaging TIRI technology permits the sensitive and rapid detection of hs-CRP high-sensitivity C-reactive protein. The whole test was complete within 10 min using -all in one step- assay with a limit of detection of 0.1 ng-mL hs-CRP. The measuring range for hs-CRP could be extended to 10 ng-mL. The chip can also be used to detect more parameters in blood samples.

KEYWORDS

Point-of-Care Testing POCT, Three Dimensional Optical Chip, hs-CRP

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Liu, C. , Cai, H. , Jia, J. , Cao, T. , Li, T. , Ma, T. and Liu, C. 2016 Point-of-Care Testing Using Three Dimensional Optical Biosensor Based on Microfluidic Technology. Journal of Biosciences and Medicines, 4, 56-61. doi: 10.4236-jbm.2016.412009.





Author: Chunxiu Liu*, Haoyuan Cai, Jian Jia, Tianyang Cao, Tong Li, Tianjun Ma, Chang Liu*

Source: http://www.scirp.org/



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