Frequency of Bacterial Organisms Isolated from Cerebrospinal Fluid CSF of Children under Five Years in Windhoek from 2010 to 2014Report as inadecuate




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Bacterial meningitis BM is a life-threatening condition which affects the central nervous system CNS. Its incidence rate is estimated between 0.22 - 2.66 and 0.81 - 6.1 cases-1000 lives worldwide and in Africa respectively. The objective of this study was to determine the frequency of bacterial organisms isolated from CSF of children less than five years old in Windhoek. A retrospective analysis was performed on 784 results of CSF submitted to the Namibia Institute of Pathology NIP from January 2010 to August 2014. The results showed that out of the suspected meningitis cases, 18 28.6% were due to Streptococcus pneumoniae, making it the frequently isolated organism, followed by Staphylococcus aureus 7 11.1%, Escherichia coli 5 7.9% and Haemophilus influenzae 4 6.3%. Streptococcus pneumoniae showed high resistance to penicillin 17 70.5% & cotrimoxazole 16 93.7% and 100% susceptibility to ciprofloxacin 5, vancomycin 13 & ceftri-axone 8. Haemophilus influenzae showed moderate resistance to cotrimoxazole 3 66% & tet-racycline 2 50%. It showed 100% sensitivity to chloramphenicol 4, cefuroxime 2 & ceftriaxone 3. Neisseria meningitidis showed high resistance to cotrimoxazole by 100% n = 2 and high sensitivity to chloramphenicol n = 2, ceftriaxone & penicillin by 100% n = 2. Streptococcus agalactiae was resistant to tetracycline and sensitive to penicillin & erythromycin by 100% n = 1. Streptococcus pneumoniae was isolated the most in this current study and it had high resistance to penicillin & cotrimoxazole. There was a significant difference between results CSF culture and PCR, Gram stain, CSF cell count, protein & glucose, as all comparisons yielded in P values less than 0.05, indicating a significant statistical association.

KEYWORDS

Bacterial Meningitis, Frequency, Cerebrospinal Fluid, Retrospective, Namibia

Cite this paper

Haimbodi, E. , Mukesi, M. , Mtambo, O. and Moyo, S. 2016 Frequency of Bacterial Organisms Isolated from Cerebrospinal Fluid CSF of Children under Five Years in Windhoek from 2010 to 2014. Open Journal of Medical Microbiology, 6, 125-132. doi: 10.4236-ojmm.2016.63017.





Author: Erastus Lafimana Haimbodi1, Munyaradzi Mukesi1*, Owen Mtambo2, Sylvester Rodgers Moyo1

Source: http://www.scirp.org/



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