Prevalence and Associations of Pseudoexfoliation Glaucoma in a Group of Tertiary Eye Care Facilities in Southwest NigeriaReport as inadecuate




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Background: Globally, glaucoma is the leading cause of irreversibleblindness. Pseudoexfoliation glaucoma is the most common form of secondary openangle glaucoma. Purpose: To determine the prevalence and characteristics of pseudoexfoliation glaucoma PXG among newlydiagnosed glaucoma patients in Eye Foundation Hospital Ikeja, Guinness EyeCenter, Lagos University Teaching Hospital and Deseret Community VisionInstitute, Ijebu Imushin. Methods: This hospital-based, descriptivecross-sectional study included newly diagnosed adult glaucoma patients at theglaucoma clinics of three tertiary eye care centers.A study proformawas used to obtain socio-demographic information, medical history, ocularhistory and relevant findings on ocular and systemic examination Descriptive andcomparative statistical analyses were performed. Values were consideredstatistically significant where P < 0.05.Results: One hundred and forty adult glaucoma patients aged 60.5 ± 11.9SD years and male to female ratio of 2:1 were examined. The prevalence of PXGamong the glaucoma patients was 16.9%. The pseudoexfoliative material PXM wasmost commonly found on the pupil 39%. Common ocular features seen among PXG patientswere poor pupillary dilation with mydriatic agents 44% and Sampaolesi’s linein the anterior chamber angle 41%. A higher proportion of PXG patients thanprimary open angle glaucoma POAG patients showed signs of severe glaucoma,including severe optic disc cupping P = 0.019 and visual field defects P =0.014. Hearing defects were the only significantly associated non-ocularfeature P = 0.0005. Conclusion: Theprevalence of PXG was 16.9%. This implies that it is relatively common in Nigeria.Hearing loss is an important non-ocular association. Careful ocular examinationof glaucoma patients is recommended to identify PXG, which runs a more severeclinical course than POAG.

KEYWORDS

Prevalence, Pseudoexfoliation Glaucoma, Pseudoexfoliation Syndrome, Nigeria

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Onochie, C. , Okoye, O. , Onakoya, A. , Ogunro, A. , Hassan, K. , Ihemedu, C. , Aribaba, T. and Okonkwo, O. 2016 Prevalence and Associations of Pseudoexfoliation Glaucoma in a Group of Tertiary Eye Care Facilities in Southwest Nigeria. Open Journal of Ophthalmology, 6, 70-79. doi: 10.4236-ojoph.2016.62010.





Author: Chizoba Onochie1, Obiekwe Okoye2*, Adeola Onakoya3, Adunola Ogunro1, Kunle Hassan1, Chidi Ihemedu4, Tade Aribaba3, Ogugua Okonkwo

Source: http://www.scirp.org/



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