The Relationship between Central Retinal Artery Resistive Index and Measures of Renal Function in Type 2 DiabetesReport as inadecuate




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Background: Renal and ocular vessels are some of the major vessels affectedin patients with diabetes, and the involvement of these vessels is independent riskfactors for other complications. Hemodynamic flow in arteries may be assessed byusing measures such as resistive index, which is a non-invasive measure of the resistancein vessels. The association between retinopathy and nephropathy has been conflicting.This study assessed the relationship between resistive index of the central retinalartery and indices of nephropathy in type 2 diabetes. Method: This cross-sectionalstudy examined 74 Nigerian diabetics who were selected consecutively from the out-patientdiabetic clinic of a tertiary hospital in South-West Nigeria. Doppler ultrasoundwas used to determine the resistive index of the central retinal artery along withthe right renal artery. The urinary and serum biochemical parameters were also doneto determine the urinary albumin excretion and the glomerular filtration rate. Results:The mean age of participants was 59.62 ± 9.55 years. The mean central retinal arteryresistive index CRARI was 0.77 ± 0.06, with 65 87.8% of the participants havingelevated CRARI. There was no statistical difference between patients with normalCRARI and elevated CRARI in respect of their urinary albumin excretion p = 0.796.There was no significant correlation between CRARI and estimated glomerular filtrationrate r = 0.120; p = 0.309 and right renal artery resistive index r = 0.068; p= 0.564. Conclusion: This study demonstrates that central retinal artery resistiveindex CRARI may not be a predictor of renal function in diabetics.

KEYWORDS

Ultrasound, Retinal Artery, Renal Function

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Ayoola, O. , Soyoye, D. , Dawha, S. , Ikem, R. , Onakpoya, O. , Adedeji, T. and Arogundade, F. 2016 The Relationship between Central Retinal Artery Resistive Index and Measures of Renal Function in Type 2 Diabetes. Journal of Diabetes Mellitus, 6, 146-151. doi: 10.4236-jdm.2016.62015.





Author: O. O. Ayoola1*, D. O. Soyoye2, S. D. Dawha1, R. T. Ikem2, O. H. Onakpoya3, T. A. Adedeji4, F. A. Arogundade2

Source: http://www.scirp.org/



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