Medical and Household Characteristics Associated with Methicillin Resistant Staphylococcus aureus Nasal Carriage among Patients Admitted to a Rural Tertiary Care HospitalReport as inadecuate




Medical and Household Characteristics Associated with Methicillin Resistant Staphylococcus aureus Nasal Carriage among Patients Admitted to a Rural Tertiary Care Hospital - Download this document for free, or read online. Document in PDF available to download.

Background

Methicillin resistant Staphylococcus aureus MRSA poses a threat to patient safety and public health. Understanding how MRSA is acquired is important for prevention efforts. This study investigates risk factors for MRSA nasal carriage among patients at an eastern North Carolina hospital in 2011.

Methods

Using a case-control design, hospitalized patients ages 18 – 65 years were enrolled between July 25, 2011 and December 15, 2011 at Vidant Medical Center, a tertiary care hospital that screens all admitted patients for nasal MRSA carriage. Cases, defined as MRSA nasal carriers, were age and gender matched to controls, non-MRSA carriers. In-hospital interviews were conducted, and medical records were reviewed to obtain information on medical and household exposures. Multivariable conditional logistic regression was used to derive odds ratio OR estimates of association between MRSA carriage and medical and household exposures.

Results

In total, 117 cases and 119 controls were recruited to participate. Risk factors for MRSA carriage included having household members who took antibiotics or were hospitalized OR: 3.27; 95% Confidence Interval CI: 1.24–8.57 and prior hospitalization with a positive MRSA screen OR: 3.21; 95% CI: 1.12–9.23. A lower proportion of cases than controls were previously hospitalized without a past positive MRSA screen OR: 0.40; 95% CI: 0.19–0.87.

Conclusion

These findings suggest that household exposures are important determinants of MRSA nasal carriage in hospitalized patients screened at admission.



Author: Leah Schinasi , Steve Wing, Pia D. M. MacDonald, David B. Richardson, Jill R. Stewart, Kerri L.Augustino, Delores L. Nobles, Keit

Source: http://plos.srce.hr/



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