The Value and the Variability of Magnetic Resonance Imaging in Patients with Systemic Lupus Erythematosus and Antiphospholipid SyndromeReport as inadecuate




The Value and the Variability of Magnetic Resonance Imaging in Patients with Systemic Lupus Erythematosus and Antiphospholipid Syndrome - Download this document for free, or read online. Document in PDF available to download.

Objectives:The objectives of this article are twofold: To review the value and thevariability of MR imaging MRI findings in patients with systemic lupuserythematosus SLE and to reveal the frequency of central nervous system CNSinvolvement. SLE is a complex multisystem autoimmune connective tissue disorderwith a broad spectrum of clinical presentations. Materials and methods: Wepresent three cases, two with neurological symptoms and one case with musculoskeletalsymptoms. Patients were imaged in the MRI department of the University Hospitalof Patras. All patients had a previous history of antiphospholipid syndrome andknown SLE. Results: None of the pts had a normal brain MRI. Abnormal lesionswere typically high on FLAIR and T2-weighted images. One patient showedmyositis of the tibial muscles bilateral and although she did not reveal anyneurological symptoms, because of the presence of APS, she underwent brain MRIto detect any cerebrovascular involvement. The brain MRI was abnormal andshowed extensive lesions and porencephalia. In all cases the differentialdiagnosis of the brain MRI included vasculitis, focal ischemia, multiplesclerosis or other entities. Parenchymal volume loss-cerebral atrophy, incompatiblewith their age, was obvious in all patients. Conclusion: Magnetic resonanceimaging is the gold standard for the investigation of central nervous system inpatients suffering from lupus. Lupus patients who also develop antiphospholipidsyndrome must be submitted to brain MRI because central nervous involvement isvery common and serious, although symptoms may be silent as in our case.

KEYWORDS

Systemic Lupus Erythematosus, Antiphospholipid Syndrome, MRI, Brain MRI

Cite this paper

Solomou, E. , Rigopoulou, A. and Petsas, T. 2015 The Value and the Variability of Magnetic Resonance Imaging in Patients with Systemic Lupus Erythematosus and Antiphospholipid Syndrome. Open Journal of Radiology, 5, 28-33. doi: 10.4236-ojrad.2015.51005.





Author: Ekaterini Solomou, Aspasia Rigopoulou*, Theodoros Petsas

Source: http://www.scirp.org/



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