Development and Characterization of Nanovesicles Containing Phenolic Compounds of Microalgae Spirulina Strain LEB-18 and Chlorella pyrenoidosaReport as inadecuate




Development and Characterization of Nanovesicles Containing Phenolic Compounds of Microalgae Spirulina Strain LEB-18 and Chlorella pyrenoidosa - Download this document for free, or read online. Document in PDF available to download.

The objective of this study was to elaborate liposomes, through thelipid film hydration methodology, to nanoencapsulate phenolic compounds of Spirulina LEB-18 and Chlorella pyrenoidosa microalgae,and evaluate their physicochemical characteristics and storage stability for 21days. The total phenolic compounds were evaluated using a calibration curve ofgallic acid using methanol and ethanol as extraction solvents. The size andpolydispersity index of nanovesicles were determined by light scattering andthe percentage encapsulation efficiency was determined by a centrifugationprocess. The stability of the liposomes at storage time was measured by zetapotential for 21 days. The methanol extracts from Spirulina had a higher content of phenolic compounds 2.62 mggallic acid·g-1 of microalgaecompared to the extracts of Chlorella. However, liposomes with ethanolic extracts of the two algae showed higherencapsulation efficiency. The valuewas higher 96.40% for Chlorella.All samples obtained nanometric size, with the highest value obtained for theliposome containing ethanol extract of Chlorella 239 nm differing significantly p ≤ 0.05 from the others. The liposomes containingextracts of Spirulina were morestable during the 21 days of storage, whereas, those consisting of ethanolextract showed no significant difference p ≤ 0.05 throughoutthis period.



KEYWORDS

Microalgae; Phenols; Encapsulation; Liposome

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L. de Assis, A. Machado, A. de Souza da Motta, J. Costa and L. de Souza-Soares -Development and Characterization of Nanovesicles Containing Phenolic Compounds of Microalgae Spirulina Strain LEB-18 and Chlorella pyrenoidosa,- Advances in Materials Physics and Chemistry, Vol. 4 No. 1, 2014, pp. 6-12. doi: 10.4236-ampc.2014.41002.





Author: Letícia Marques de Assis, Adriana Rodrigues Machado, Amanda de Souza da Motta, Jorge Alberto Vieira Costa, Leonor Almeida de Sou

Source: http://www.scirp.org/



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