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The aim of this study is to apply the NutrientAnalysis Critical Control Point NACCP process to ensure that the highestnutrient levels in food can determine a beneficial effect on the health of theconsumer. The NACCP process involves a sequence of analysis and controls thatdepart from raw material production to the evaluation of the effect ofnutrition on health. It is articulated through the following points: 1 identification of nutrient level in the food; 2 identification of critical control pointsenvironmental, genetic data, chemical and physical data, productiontechnology, distribution and administration; 3 establishing critical limits that can impoverish and damagethe nutrient; 4 establishing measures to monitor; 5 establishing correctiveactions. We selected as biomarkers thetotal phenolic content TPC and total antioxidant capacity TAC of a genotyped Italian hazelnut cultivars Corylus e avellana L

Weperformed a clinical study evaluating: anutritional status; bclinical-biochemical parameters; clow density lipoprotein oxidation LDL-ox; d the expression level changes ofoxidative stress pathway genes in the blood cell at baseline and after 40 g-die of hazelnutconsumption. In this study, we found a significant lowering p ≤ 0.005 of LDLoxidized proteins, in association with the consumption of 40 g-d of hazelnuts.Also, we found a significant variation p ≤ 0.005 of gene expression of antioxidant andpro-oxidant genes, between the intake of dietary with and without hazelnuts.This results support the hypothesis that the NACCP process could be applied toobtain significant benefits in terms of primary prevention and for contributing to the amelioration of food management atthe consumer level.

KEYWORDS

NACCP Process; Hazelnut; Nutrigenomic; Oxidative Stress; LDL-Oxidation

Cite this paper

Renzo, L. , Carraro, A. , Minella, D. , Botta, R. , Contessa, C. , Sartor, C. , Iacopino, A. and Lorenzo, A. 2014 Nutrient Analysis Critical Control Point NACCP: Hazelnut as a Prototype of Nutrigenomic Study. Food and Nutrition Sciences, 5, 79-88. doi: 10.4236-fns.2014.51011.





Author: Laura Di Renzo, Alberto Carraro, Daniela Minella, Roberto Botta, Cecilia Contessa, Chiara Sartor, Anna Maria Iacopino, Antonino D

Source: http://www.scirp.org/



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