The Prevalence of Parasitic Human Intestinal Helminthes and the Efficacy of Anthelmintic Drug in Children in Uzo-Uwani Local Government Area, Enugu State, NigeriaReport as inadecuate




The Prevalence of Parasitic Human Intestinal Helminthes and the Efficacy of Anthelmintic Drug in Children in Uzo-Uwani Local Government Area, Enugu State, Nigeria - Download this document for free, or read online. Document in PDF available to download.

Introduction: A study on the current status of parasitic intestinal helminthes and the efficacy of anthelmintic drug was carried out among primary school pupils at Community Primary School Ogurugu, Uzo-Uwani Local Government Area, Enugu State. Objectives: The research was conducted in order to determine the prevalence of human intestinal helminthes among primary school pupils, and also to determine the prevalence in relation to age and sex, and to check the efficacy of anthelmintic drug Levamisole on the worms, in Ogurugu Uzo-Uwani Local Government Area, Enugu State, Nigeria. Methods: A total of 242 faecal samples were collected randomly from the school children and analyzed using standard parasitological procedures. Results: Data obtained showed an overall prevalence of 143 59.1% out of 242 samples and that the efficacy of anthelmintic drug Ergamisole? Levamisole R12564; Unicure Pvt.ltd India 50 mg in reducing the worm burden was 99 82.5% in 120 samples treated. Age related prevalence and efficacy of anthelmintic varied across the sample groups. There was no significant difference in sex related infections in the sample group P > 0.5. The efficacy of the drug reduces with the increase in age. Also the efficacy of Levamisole drug in reducing the worm burden were hookworm 59 89.5%, Ascaris 24 85.7%, Trichuris 26 78.6% while Taenia and Strongyloides showed drug resistance. This indicates that a single dose of the medication is not enough for total elimination of these endo parasites. Conclusion: The study revealed that poor hygienic practices as well as unsanitary conditions were responsible for high prevalence recorded in the area, and advocated health education through primary health care and mass deworming of primary school children as control measures.

KEYWORDS

Prevalence; Anthelmintic; Levamisole; Children; Ascaris lumbricoides; Trichuris trichiura

Cite this paper

C. Ukwubile, O. Otalu Jr., U. Akpabio and M. Agu -The Prevalence of Parasitic Human Intestinal Helminthes and the Efficacy of Anthelmintic Drug in Children in Uzo-Uwani Local Government Area, Enugu State, Nigeria,- Open Journal of Medical Microbiology, Vol. 3 No. 4, 2013, pp. 213-218. doi: 10.4236-ojmm.2013.34032.





Author: Cletus Anes Ukwubile1*, Otalu Otalu Jr.3, Uduak Akpabio3, Matthew Onyema Agu2

Source: http://www.scirp.org/



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