Detection of Extended Spectrum β-Lactamase Producing Klebsiella pneumoniae and Escherichia coli in Two Hospitals in the Federal Capital Territory, Abuja, NigeriaReport as inadecuate




Detection of Extended Spectrum β-Lactamase Producing Klebsiella pneumoniae and Escherichia coli in Two Hospitals in the Federal Capital Territory, Abuja, Nigeria - Download this document for free, or read online. Document in PDF available to download.

In this study, the prevalence of Extended Spectrum Beta-lactamase ESBL producing Klebsiella pneumoniae and Escherichia coli isolates from the University of Abuja Teaching Hospital and the National Hospital was determined. A total of two hundred and fifteen 215 clinical isolates were examined, of which 60% were E. coli and 40% K. pneumoniae respectively. The isolates were collected from various samples namely: Stool, Urine, Pus, High Vagina Swab, Sputum and Wound swab. Out of these isolates, 54 of K. pneumoniae were screened to be ESBL negative and 32 as ESBL positive isolates, while 88 and 40 E. coli were also screened as ESBL negative and ESBL positive isolates respectively. These represent 37.9% of all K. pneumoniae isolates and 31.25% of E. coli isolates respectively. The prevalence of ESBL among the species was not however statistically different p > 0.05. Multiple resistance in these isolates was common and there is the need for routine screening of ESBL in our hospitals to guide rational and effective use of antibiotics.

KEYWORDS

Extended Spectrum Beta-Lactamase; Klebsiella pneumoniae; Escherichia coli; Nigeria; Multidrug Resistance

Cite this paper

B. Akanbi, B. Ojonuba and R. Njoku -Detection of Extended Spectrum β-Lactamase Producing Klebsiella pneumoniae and Escherichia coli in Two Hospitals in the Federal Capital Territory, Abuja, Nigeria,- Open Journal of Medical Microbiology, Vol. 3 No. 4, 2013, pp. 207-212. doi: 10.4236-ojmm.2013.34031.





Author: Bolaji Oluwatosin Akanbi, Benjamin Destiny Ojonuba, Remi Njoku

Source: http://www.scirp.org/



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