Does Surgery Have a Relevant Role in the Primary Treatment of Locoregionally Advanced Oropharyngeal CarcinomasReport as inadecuate




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Background: Treatment concepts for oropharyngeal squamous cell carcinomas arecontroversial. This review compares the results obtained by distinct treatmentoptions in locoregionally oropharyngeal advanced carcinomas: primary surgicalresection followed by concurrent chemoradiotherapy and concurrentchemoradiotherapy alone. Methods: 57patients with stage III and IV oropharyngeal squamous cell carcinomawere selected. 17 patients were treated with primary surgicalresection followed by concurrent chemoradiotherapy and 40 patients were treatedonly with concurrent chemoradiotherapy. Statistical analysis was performedregarding survival rates according to tumor location, stage, treatment regimenand recurrence. Results: Two-yearloco-regional control rates were 94% after surgery plus chemoradiotherapyand 55% after chemoradiotherapy p = 0.016. Progression free survival rates were88% and 27%, respectively p



Author: Joana Guimarães, Sara Cruz, Eduardo Breda, Eurico Monteiro

Source: http://www.scirp.org/



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