Developing Customized Evaluation Software for Clinical Trials: An Example with Obstructive Lung DiseasesReport as inadecuate




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Corresponding customized software tool is usuallyunavailable, which increases the time and workload for evaluating the resultsof a clinical trial. In the present paper, we demonstrate the developmentprocess of a customized software for one clinical trial on patients withobstructive lung disease. Over hundred patients and volunteers as controlledwere included in the clinical trial. They were examined by spirometry and EITin a seated position during spontaneous tidal breathing. Subsequently, standardvital capacity maneuver and forced full expiration maneuver were performed. Inorder to evaluate the offline data, a customized software wasdeveloped. The requirements of the software were defined by investigators. Thesoftware was then tested on patients’ data and refined based on feedbacks ofthe investigators. We finalized the customized software with analysis of variousdisease-specific parameters and indices. Compared to the data process withdevice specific programs and other commercial software, the customized softwareis more flexible, user-friendly and extendable. As conclusion, customizedsoftware simplifies the evaluation process distinctly and helps physicians tofocus on study design and result interpretation.







KEYWORDS

Clinical Trial; Electrical Impedance Tomography; Pulmonary Function Test; Customized Software

Cite this paper

Zhao, Z. , Vogt, B. , Frerichs, I. , Müller-Lisse, U. and Möller, K. 2013 Developing Customized Evaluation Software for Clinical Trials: An Example with Obstructive Lung Diseases. Engineering, 5, 103-107. doi: 10.4236-eng.2013.510B021.





Author: Zhanqi Zhao, Barbara Vogt, Inéz Frerichs, Ullrich Müller-Lisse, Knut Möller

Source: http://www.scirp.org/



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