A Study of Antifungal and Antiafl atoxigenic Action of Newly Synthesized Analogues of Dehydroacetic AcidReport as inadecuate




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Croatian journal of food technology, biotechnology and nutrition, Vol.5 No.3-4 December 2010. -

Mycelial growth and afl atoxin B1 accumulation by toxigenous mould Aspergillus flavus were inhibited by dehydroacetic acid and its newly

synthesized analogues, 4-hydroxy-3-p-toluoyl-6-p-tolil-2H-yrane-2-one DHT and 5-Bromo-4-hydroxy-3-p-toluoyl-6-p-tolil-2Hpyrane-2-one BrDHT during the growth of investigated mould on solid substrate soy-beans. Experiments were carried out in a stationary culture at 20 0C and 30 0C, respectively, during 21 days. Mycelial growth biomass dry weight was determined by measuring the chitin content and concentration of afl atoxin B1 AFB1 was quantitated by HPLC. Concentrations of DHA and

DHT of 0.1 and 0.2 μg x g-1 of substrate were stimulated, but concentrations higher than 0.5 μg x g-1 of these compounds, mould growth and AFB1 accumulation partially inhibited. In experiments with 0.2 μg x g-1 of BrDHT mould growth and AFB1 accumulation were inhibited completely depending on the time and temperature of cultivation.

toxigenous moulds; aflatoxin B1; dehydroacetic acid; chitin; HPLC



Author: Duarković Lejla - ; Faculty of Food Technology and Biotechnology, Zagreb, Croatia Mihaela Blažinkov - ; Faculty of Agriculture,

Source: http://hrcak.srce.hr/



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