CT Perfusion and Noncontrast CT in Acute Ischemic Stroke Diagnosing – Is there Influence on early Thrombolytic Therapy OutcomeReport as inadecuate




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Collegium antropologicum, Vol.34 No.4 December 2010. -

The objective of this study was to compare noncontrast computed tomography NCCT and computed tomography perfusion CTP in early diagnosis of acute ischemic stroke and to define influence of these diagnostic procedures on early outcome of thrombolytic therapy TLTH. The study included 45 patients, 35 patients submitted to NCCT and CTP and 10 patients who underwent only NCCT, before CTP was introduced. Based on the National Institute of Health Stroke Scale NIHSS score we compared early outcome of patients who received TLTH after NCCT only group 1 with the early outcome of patients who received TLTH following NCCT and CTP group 2. Statistically significant difference was found in acute stroke diagnosing between CTP and NCCT p=0.002. There were no statistically significant differences in TLTH early outcome between group 1 and group 2. In conclusion, CTP should be done regulary in patients presenting with acute ischemic stroke symptoms. More research needs to be done in defining exact influence of CTP implementation on the TLTH outcome.

stroke; computed tomography; perfusion; penumbra; thrombolytic therapy



Author: Stipan Janković - Mirela Pavičić Ivelja - Krešimir Kolić - Ante Buča - Krešimir Dolić - Sanja Lovrić Kojundžić - Kreš

Source: http://hrcak.srce.hr/



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