Isolation of Hox Cluster Genes from Insects Reveals an Accelerated Sequence Evolution RateReport as inadecuate




Isolation of Hox Cluster Genes from Insects Reveals an Accelerated Sequence Evolution Rate - Download this document for free, or read online. Document in PDF available to download.

Among gene families it is the Hox genes and among metazoan animals it is the insects Hexapoda that have attracted particular attention for studying the evolution of development. Surprisingly though, no Hox genes have been isolated from 26 out of 35 insect orders yet, and the existing sequences derive mainly from only two orders 61% from Hymenoptera and 22% from Diptera. We have designed insect specific primers and isolated 37 new partial homeobox sequences of Hox cluster genes lab, pb, Hox3, ftz, Antp, Scr, abd-a, Abd-B, Dfd, and Ubx from six insect orders, which are crucial to insect phylogenetics. These new gene sequences provide a first step towards comparative Hox gene studies in insects. Furthermore, comparative distance analyses of homeobox sequences reveal a correlation between gene divergence rate and species radiation success with insects showing the highest rate of homeobox sequence evolution.



Author: Heike Hadrys , Sabrina Simon, Barbara Kaune, Oliver Schmitt, Anja Schöner, Wolfgang Jakob, Bernd Schierwater

Source: http://plos.srce.hr/



DOWNLOAD PDF




Related documents