Hodgkin’s Lymphoma Variant of Richter’s SyndromeReport as inadecuate

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Collegium antropologicum, Vol.34 No.1 March 2010. -

Chronic lymphocytic leukemia-small lymphocitic lymphoma CLL-SLL is low-grade malignant lymphoprolipheration, that has tendency to conwert to a higher-grade neoplasam over time. More common is the development of a diffuse large cell lymphoma or transformation into prolymphocytic cell population. In rare cases, 0.1–0.5% of patients develop multiple myeloma or Hodgkin’s disease. We present 65-year old female with Hodgkin’s variant of Richter’s syndrome. On the basis of clinical simptoms, cytological, hystological and immunohistological finding in April 2008 CLL-SLL were diagnosed. The patient was treated with 8 courses of R-CHOP. After 10 month, FNA of the one of the enlarged lymph node on the neck was performed. The diagnosis was Hodgkin’s disease. Immuno-hystological studies of the lymph node was consistent with type I Hodgkin’s type of Richter’s syndrome. Patient was treated with 3 courses of ABVD and radiotherap.

Richter’s syndrome; chronic lymphocytic leukemia; Hodgkin’s disease; Reed-Sternberg cell

Author: Ankica Vasilj - ; Department of Cytology, University Clinic of Internal Medicine, University Hospital »Sestre Milosrdnice«, Zag

Source: http://hrcak.srce.hr/


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