Polycystic Ovarian Syndrome: Clinical Correlation with Biochemical StatusReport as inadecuate




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Objective: To find out the correlation between various biochemical and clinical features of polycystic ovarian syndrome and to determine the best hormonal marker for the same. Material and Methods: The study included 100 patients of polycystic ovary syndrome 50 married & 50 unmarried and a control group comprising of 50 women 25 married & 25 unmarried in the age group of 18 - 30 years. The pregnant females and those having hyperandrogenism due to any other endocrine disorders were excluded. Results: Mean age was 27.66 years in the married study group and 25.46 years in the unmarried study group. About 71% of patients had oligomenorrhea. It significantly correlated with raised LH:FSH ratio and raised total testosterone levels. Body mass index was raised >25 kg-m2 in 66.7% married and 72.66% unmarried patients in study group and in 22% in control group. 95% of the patients in the study group and 4% in the control group were detected to have polycystic ovaries on ultrasonography. 62% of the patients had raised LH levels; total testosterone was elevated in 57.7%. The LH:FSH ratio was raised in 41% in study group patients more in the unmarried group 56% than in married group 26%. 20% of patients in the control group had an elevated LH:FSH ratio. Total testosterone level was elevated in 60% of our patients. None of the patient in the control group had elevated testosterone levels. About 31% of the patients in study group were hirsute. Conclusion: Hormonal values correlate well with polycystic ovarian syndrome and serum total testosterone served as the best hormonal marker for such patients.

KEYWORDS

Polycystic Ovarian Syndrome; Hormonal Analysis; Clinical Correlation; Best Marker

Cite this paper

R. Yousouf, M. Khan, Z. Kounsar, S. Ahangar and W. Lone -Polycystic Ovarian Syndrome: Clinical Correlation with Biochemical Status,- Surgical Science, Vol. 3 No. 5, 2012, pp. 245-248. doi: 10.4236-ss.2012.35048.





Author: Rahila Yousouf, Musadiq Khan, Zeenat Kounsar, Shahnawaz Ahangar, Wasim Abdullah Lone

Source: http://www.scirp.org/



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